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Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents

Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,b (obtained from the reaction of ethyl 3-oxo-2-(2-arylhydrazono)butanoates 1a,b with thiosemicarbazide) could be transfor...

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Detalles Bibliográficos
Autores principales: Sayed, Abdelwahed R., Gomha, Sobhi M., Abdelrazek, Fathy M., Farghaly, Mohamed S., Hassan, Shaimaa A., Metz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760062/
https://www.ncbi.nlm.nih.gov/pubmed/31572983
http://dx.doi.org/10.1186/s13065-019-0632-5