Construction of a novel quinoxaline as a new class of Nrf2 activator

BACKGROUND: The transcription factor Nuclear factor erythroid-2-related factor 2 (NRF2) and its principal repressive regulator, Kelch-like ECH-associated protein 1 (KEAP1), are perilous in the regulation of inflammation, as well as maintenance of homeostasis. Thus, NRF2 activation is involved in cyt...

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Detalles Bibliográficos
Autores principales: Kandasamy, Murugesh, Mak, Kit-Kay, Devadoss, Thangaraj, Thanikachalam, Punniyakoti Veeraveedu, Sakirolla, Raghavendra, Choudhury, Hira, Pichika, Mallikarjuna Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760105/
https://www.ncbi.nlm.nih.gov/pubmed/31572984
http://dx.doi.org/10.1186/s13065-019-0633-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760105/
https://www.ncbi.nlm.nih.gov/pubmed/31572984
http://dx.doi.org/10.1186/s13065-019-0633-4

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