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Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy

The exchange proteins directly activated by cAMP 1 and 2 (Epac1 and Epac2) are expressed in a cell specific manner in the liver, but their biological functions in this tissue are poorly understood. The current study was undertaken to begin to determine the potential roles of Epac1 and Epac2 in liver...

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Detalles Bibliográficos
Autores principales: Sivertsen Åsrud, Kathrine, Pedersen, Line, Aesoy, Reidun, Muwonge, Haruna, Aasebø, Elise, Nitschke Pettersen, Ina Katrine, Herfindal, Lars, Dobie, Ross, Jenkins, Stephen, Berge, Rolf Kristian, Henderson, Neil Cowan, Selheim, Frode, Døskeland, Stein Ove, Bakke, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760117/
https://www.ncbi.nlm.nih.gov/pubmed/31551444
http://dx.doi.org/10.1038/s41598-019-50219-8