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Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its outer membrane vesicle component

The capsular group B meningococcal (MenB) four component vaccine (4CMenB) has been licensed for the prevention of invasive disease caused by MenB. The vaccine causes fever in infants, particularly when given in combination (concomitant) with other routinely-administered vaccines (routine), such as t...

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Detalles Bibliográficos
Autores principales: Sheerin, Dylan, O’Connor, Daniel, Dold, Christina, Clutterbuck, Elizabeth, Attar, Moustafa, Rollier, Christine S., Sadarangani, Manish, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760121/
https://www.ncbi.nlm.nih.gov/pubmed/31551511
http://dx.doi.org/10.1038/s41598-019-50310-0