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No evidence for viral small RNA production and antiviral function of Argonaute 2 in human cells

RNA interference (RNAi) has strong antiviral activity in a range of animal phyla, but the extent to which RNAi controls virus infection in chordates, and specifically mammals remains incompletely understood. Here we analyze the antiviral activity of RNAi against a number of positive-sense RNA viruse...

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Detalles Bibliográficos
Autores principales: Schuster, Susan, Overheul, Gijs J., Bauer, Lisa, van Kuppeveld, Frank J. M., van Rij, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760161/
https://www.ncbi.nlm.nih.gov/pubmed/31551491
http://dx.doi.org/10.1038/s41598-019-50287-w