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The transferability of lipid loci across African, Asian and European cohorts

Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populations. Genetic correlations for lipids between European-ancestry and Asian cohorts are not significan...

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Detalles Bibliográficos
Autores principales: Kuchenbaecker, Karoline, Telkar, Nikita, Reiker, Theresa, Walters, Robin G., Lin, Kuang, Eriksson, Anders, Gurdasani, Deepti, Gilly, Arthur, Southam, Lorraine, Tsafantakis, Emmanouil, Karaleftheri, Maria, Seeley, Janet, Kamali, Anatoli, Asiki, Gershim, Millwood, Iona Y., Holmes, Michael, Du, Huaidong, Guo, Yu, Kumari, Meena, Dedoussis, George, Li, Liming, Chen, Zhengming, Sandhu, Manjinder S., Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760173/
https://www.ncbi.nlm.nih.gov/pubmed/31551420
http://dx.doi.org/10.1038/s41467-019-12026-7