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Human Urinary mRNA as a Biomarker of Cardiovascular Disease: A Proof-of-Principle Study of Sodium Loading in Prehypertension

BACKGROUND: mRNA in urine supernatant (US-mRNA) might encode information about renal and cardiorenal pathophysiology, including hypertension. H, whether the US-mRNA transcriptome reflects that of renal tissues and whether changes in renal physiology are detectable using US-mRNA is unknown. METHODS:...

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Detalles Bibliográficos
Autores principales: Bazzell, Brian G., Rainey, William E., Auchus, Richard J., Zocco, Davide, Bruttini, Marco, Hummel, Scott L., Byrd, James Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760265/
https://www.ncbi.nlm.nih.gov/pubmed/30354328
http://dx.doi.org/10.1161/CIRCGEN.118.002213