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Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy

Cellular therapies based on mesenchymal stromal/stem cells (MSC) are promising strategies in regenerative medicine and oncology. Despite encouraging results, there is still some level of concerns on inoculating MSC in cancer patients. To face this issue, one possibility resides in engineering MSC by...

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Detalles Bibliográficos
Autores principales: Rossignoli, Filippo, Grisendi, Giulia, Spano, Carlotta, Golinelli, Giulia, Recchia, Alessandra, Rovesti, Giulia, Orsi, Giulia, Veronesi, Elena, Horwitz, Edwin M., Dominici, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760542/
https://www.ncbi.nlm.nih.gov/pubmed/29955091
http://dx.doi.org/10.1038/s41417-018-0034-1