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Genetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesity

OBJECTIVES: To comprehensively explore metabolic and genetic contributors to liver fat accumulation in overweight/obese children. METHODS: Two hundred thirty Italian children with obesity were investigated for metabolic parameters and genotyped for PNPLA3, TM6SF2, GCKR, and MBOAT7 gene variants. Per...

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Detalles Bibliográficos
Autores principales: Di Costanzo, Alessia, Pacifico, Lucia, Chiesa, Claudio, Perla, Francesco Massimo, Ceci, Fabrizio, Angeloni, Antonio, D’Erasmo, Laura, Di Martino, Michele, Arca, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760560/
https://www.ncbi.nlm.nih.gov/pubmed/30710115
http://dx.doi.org/10.1038/s41390-019-0303-1