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MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells

Previously, we demonstrated that Prx II is important for survival of the gefitinib-resistant A549 (A549/GR) cell line, an NSCLC cell line derived by repeated exposure to gefitinib. Therefore, in this study, we used A549/GR cells to investigate the role of Prx II in GR NSCLC stemness. Initially, to e...

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Detalles Bibliográficos
Autores principales: Chandimali, Nisansala, Huynh, Do Luong, Zhang, Jiao Jiao, Lee, Jae Cheol, Yu, Dae-Yeul, Jeong, Dong Kee, Kwon, Taeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760639/
https://www.ncbi.nlm.nih.gov/pubmed/30341415
http://dx.doi.org/10.1038/s41417-018-0050-1