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S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients

In biological tissues, radiation causes the formation of reactive oxygen species (ROS), some of which lead to sequential oxidation of certain protein cysteine residues. Resultant cysteinyl radicals are subject to post-translational modification through S-glutathionylation. The present clinical trial...

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Detalles Bibliográficos
Autores principales: Zhang, Leilei, Zhang, Jie, Ye, Zhiwei, Manevich, Yefim, Townsend, Danyelle M., Marshall, David T., Tew, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760651/
https://www.ncbi.nlm.nih.gov/pubmed/31551460
http://dx.doi.org/10.1038/s41598-019-50288-9