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Imaging disease activity of rheumatoid arthritis by macrophage targeting using second generation translocator protein positron emission tomography tracers

BACKGROUND: Positron emission tomography (PET) imaging of macrophages using the translocator protein (TSPO) tracer (R)-[(11)C]PK11195 has shown the promise to image rheumatoid arthritis (RA). To further improve TSPO PET for RA imaging, second generation TSPO tracers [(11)C]DPA-713 and [(18)F]DPA-714...

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Detalles Bibliográficos
Autores principales: Bruijnen, S. T. G., Verweij, N. J. F., Gent, Y. Y. J., Huisman, M. C., Windhorst, A. D., Kassiou, M., van de Ven, P. M., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E., van der Laken, C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760780/
https://www.ncbi.nlm.nih.gov/pubmed/31553762
http://dx.doi.org/10.1371/journal.pone.0222844