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Investigation Of Vitamin B(12)-Modified Amphiphilic Sodium Alginate Derivatives For Enhancing The Oral Delivery Efficacy Of Peptide Drugs

PURPOSE: Peptide drugs have been used in therapy various diseases. However, the poor bioavailability of peptide drugs for oral administration has limited their clinical applications, on account of the acidic environment and digestive enzymes inside the human gastrointestinal tract. To enhance stabil...

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Detalles Bibliográficos
Autores principales: Long, Lingli, Lai, Minghua, Mao, Xuhong, Luo, Jiahao, Yuan, Xin, Zhang, Li-Ming, Ke, Zunfu, Yang, Liqun, Deng, David YB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760826/
https://www.ncbi.nlm.nih.gov/pubmed/31571874
http://dx.doi.org/10.2147/IJN.S218944