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Investigation Of Vitamin B(12)-Modified Amphiphilic Sodium Alginate Derivatives For Enhancing The Oral Delivery Efficacy Of Peptide Drugs
PURPOSE: Peptide drugs have been used in therapy various diseases. However, the poor bioavailability of peptide drugs for oral administration has limited their clinical applications, on account of the acidic environment and digestive enzymes inside the human gastrointestinal tract. To enhance stabil...
Autores principales: | Long, Lingli, Lai, Minghua, Mao, Xuhong, Luo, Jiahao, Yuan, Xin, Zhang, Li-Ming, Ke, Zunfu, Yang, Liqun, Deng, David YB |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760826/ https://www.ncbi.nlm.nih.gov/pubmed/31571874 http://dx.doi.org/10.2147/IJN.S218944 |
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