Chondro-protective effects of polydatin in osteoarthritis through its effect on restoring dysregulated autophagy via modulating MAPK, and PI3K/Akt signaling pathways

Osteoarthritis (OA) is a degenerative disease of the cartilage that is prevalent in the middle-aged and elderly demography. Polydatin (PD), a natural resveratrol glucoside, has shown significant anti-inflammatory and anti-arthritic potential in previous studies. This study was designed to evaluate t...

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Detalles Bibliográficos
Autores principales: Wu, Zhengyuan, Luan, Zhiwei, Zhang, Xiaohan, Zou, Kai, Ma, Shiting, Yang, Zhenyi, Feng, Wenyu, He, Mingwei, Jiang, Linhua, Li, Jia, Yao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761091/
https://www.ncbi.nlm.nih.gov/pubmed/31554953
http://dx.doi.org/10.1038/s41598-019-50471-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761091/
https://www.ncbi.nlm.nih.gov/pubmed/31554953
http://dx.doi.org/10.1038/s41598-019-50471-y

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