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MicroRNA-27a/b-3p and PPARG regulate SCAMP3 through a feed-forward loop during adipogenesis

MicroRNAs (miRNA) modulate gene expression through feed-back and forward loops. Previous studies identified miRNAs that regulate transcription factors, including Peroxisome Proliferator Activated Receptor Gamma (PPARG), in adipocytes, but whether they influence adipogenesis via such regulatory loops...

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Detalles Bibliográficos
Autores principales: Kulyté, Agné, Kwok, Kelvin Ho Man, de Hoon, Michiel, Carninci, Piero, Hayashizaki, Yoshihide, Arner, Peter, Arner, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761119/
https://www.ncbi.nlm.nih.gov/pubmed/31554889
http://dx.doi.org/10.1038/s41598-019-50210-3