Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells

Age-related tissue alterations have been associated with a decline in stem cell number and function. Although increased cell-to-cell variability in transcription or epigenetic marks has been proposed to be a major hallmark of ageing, little is known about the molecular diversity of stem cells during...

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Detalles Bibliográficos
Autores principales: Hernando-Herraez, Irene, Evano, Brendan, Stubbs, Thomas, Commere, Pierre-Henri, Jan Bonder, Marc, Clark, Stephen, Andrews, Simon, Tajbakhsh, Shahragim, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761124/
https://www.ncbi.nlm.nih.gov/pubmed/31554804
http://dx.doi.org/10.1038/s41467-019-12293-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761124/
https://www.ncbi.nlm.nih.gov/pubmed/31554804
http://dx.doi.org/10.1038/s41467-019-12293-4

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