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CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex

Age Related Macular Degeneration (AMD) is the first cause of social blindness in people aged over 65 leading to atrophy of retinal pigment epithelial cells (RPE), photoreceptors and choroids, eventually associated with choroidal neovascularization. Accumulation of undigested cellular debris within R...

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Detalles Bibliográficos
Autores principales: Borras, Céline, Canonica, Jérémie, Jorieux, Sylvie, Abache, Toufik, El Sanharawi, Mohamed, Klein, Christophe, Delaunay, Kimberley, Jonet, Laurent, Salvodelli, Michèle, Naud, Marie-Christine, Arsenijevic, Yvan, Shalabi, Andrée, Souchaud, Landry, Behar-Cohen, Francine, Dinet, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761137/
https://www.ncbi.nlm.nih.gov/pubmed/31554875
http://dx.doi.org/10.1038/s41598-019-50420-9