Cargando…

CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex

Age Related Macular Degeneration (AMD) is the first cause of social blindness in people aged over 65 leading to atrophy of retinal pigment epithelial cells (RPE), photoreceptors and choroids, eventually associated with choroidal neovascularization. Accumulation of undigested cellular debris within R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borras, Céline, Canonica, Jérémie, Jorieux, Sylvie, Abache, Toufik, El Sanharawi, Mohamed, Klein, Christophe, Delaunay, Kimberley, Jonet, Laurent, Salvodelli, Michèle, Naud, Marie-Christine, Arsenijevic, Yvan, Shalabi, Andrée, Souchaud, Landry, Behar-Cohen, Francine, Dinet, Virginie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761137/ https://www.ncbi.nlm.nih.gov/pubmed/31554875 http://dx.doi.org/10.1038/s41598-019-50420-9

Ejemplares similares

Mechanisms of FH Protection Against Neovascular AMD
por: Borras, Céline, et al.
Publicado: (2020)

Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics
por: Dinet, Virginie, et al.
Publicado: (2016)

Meteorin Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration
por: Delaunay, Kimberley, et al.
Publicado: (2021)

ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy
por: Rothschild, Pierre-Raphaël, et al.
Publicado: (2017)

Pathogenic Effects of Mineralocorticoid Pathway Activation in Retinal Pigment Epithelium
por: Canonica, Jérémie, et al.
Publicado: (2021)

Effects of rat anti-VEGF antibody in a rat model of corneal graft rejection by topical and subconjunctival routes
por: Rocher, Nicolas, et al.
Publicado: (2011)

Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions
por: Daruich, Alejandra, et al.
Publicado: (2016)

Comparative Analysis of Urso- and Tauroursodeoxycholic Acid Neuroprotective Effects on Retinal Degeneration Models
por: Daruich, Alejandra, et al.
Publicado: (2022)

Influence of CFH gene on symptom severity of schizophrenia
por: Zhang, Chen, et al.
Publicado: (2017)

Molecular Docking and Molecular Dynamics (MD) Simulation of Human Anti-Complement Factor H (CFH) Antibody Ab42 and CFH Polypeptide
por: Yang, Bing, et al.
Publicado: (2019)

Nestin contributes to laser choroidal and retinal neovascularization
por: Miloudi, Sofiane, et al.
Publicado: (2022)

Long-Term Oral Treatment with Non-Hypoglycemic Dose of Glibenclamide Reduces Diabetic Retinopathy Damage in the Goto-KakizakiRat Model
por: Berdugo, Marianne, et al.
Publicado: (2021)

Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model
por: Daruich, Alejandra, et al.
Publicado: (2021)

Atypical HUS Associated with CFH/CFHR-1 Hybrid Gene
por: Negi, Sharon, et al.
Publicado: (2020)

Exogenous CFH Modulates Levels of Pro-Inflammatory Mediators to Prevent Oxidative Damage of Retinal Pigment Epithelial Cells with the At-Risk CFH Y402H Variant
por: Velazquez-Soto, Henry, et al.
Publicado: (2023)

Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection
por: Daruich, Alejandra, et al.
Publicado: (2019)

Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation
por: Decembrini, Sarah, et al.
Publicado: (2017)

Anti-vascular endothelial growth factor acts on retinal microglia/macrophage activation in a rat model of ocular inflammation
por: Couturier, Aude, et al.
Publicado: (2014)

The Aldosterone-Mineralocorticoid Receptor Pathway Exerts Anti-Inflammatory Effects in Endotoxin-Induced Uveitis
por: Bousquet, Elodie, et al.
Publicado: (2012)

Interleukin 27 Induces the Expression of Complement Factor H (CFH) in the Retina
por: Amadi-Obi, Ahjoku, et al.
Publicado: (2012)

An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations
por: Potic, Jelena, et al.
Publicado: (2020)

Glial cells of the human fovea
por: Delaunay, Kimberley, et al.
Publicado: (2020)

Association of CFH and CFB Gene Polymorphisms with Retinopathy in Type 2 Diabetic Patients
por: Wang, Jun, et al.
Publicado: (2013)

Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis
por: Gouda, Heba R., et al.
Publicado: (2022)

The protective role of transferrin in Müller glial cells after iron-induced toxicity
por: Picard, Emilie, et al.
Publicado: (2008)

Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice
por: Picard, Emilie, et al.
Publicado: (2010)

The activation of the atypical PKC zeta in light-induced retinal degeneration and its involvement in L-DNase II control
por: Jaadane, Imene, et al.
Publicado: (2015)

CFH 184G as a genetic risk marker for anterior uveitis in Chinese females
por: Yang, Ming-ming, et al.
Publicado: (2011)

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients
por: McCormack, Mark, et al.
Publicado: (2018)

A haplotype in CFH family genes confers high risk of rare glomerular nephropathies
por: Ding, Yin, et al.
Publicado: (2017)

Associations of ARMS2 and CFH Gene Polymorphisms with Neovascular Age-Related Macular Degeneration
por: Supanji, Supanji, et al.
Publicado: (2021)

CFH I62V as a Putative Genetic Marker for Posner-Schlossman Syndrome
por: Yang, Ming Ming, et al.
Publicado: (2021)

CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome
por: Sugawara, Yuka, et al.
Publicado: (2023)

PKCζ Mediates Breakdown of Outer Blood-Retinal Barriers in Diabetic Retinopathy
por: Omri, Samy, et al.
Publicado: (2013)

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration
por: Raychaudhuri, Soumya, et al.
Publicado: (2011)

The effect of CFH polymorphisms on the response to the treatment of age-related macular degeneration (AMD) with intravitreal ranibizumab
por: Dikmetas, Ozlem, et al.
Publicado: (2013)

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy
por: Hosoda, Yoshikatsu, et al.
Publicado: (2018)

Deleterious Impact of a Novel CFH Splice Site Variant in Atypical Hemolytic Uremic Syndrome
por: Schönauer, Ria, et al.
Publicado: (2019)

Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis
por: Li, Lin-Lin, et al.
Publicado: (2023)

Chronic Systemic Dexamethasone Regulates the Mineralocorticoid/Glucocorticoid Pathways Balance in Rat Ocular Tissues
por: Zola, Marta, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r7e7meju0m69ml9902l6uauns2