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Massive computational acceleration by using neural networks to emulate mechanism-based biological models

For many biological applications, exploration of the massive parametric space of a mechanism-based model can impose a prohibitive computational demand. To overcome this limitation, we present a framework to improve computational efficiency by orders of magnitude. The key concept is to train a neural...

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Detalles Bibliográficos
Autores principales: Wang, Shangying, Fan, Kai, Luo, Nan, Cao, Yangxiaolu, Wu, Feilun, Zhang, Carolyn, Heller, Katherine A., You, Lingchong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761138/
https://www.ncbi.nlm.nih.gov/pubmed/31554788
http://dx.doi.org/10.1038/s41467-019-12342-y