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L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

The combination of in vitro multi-electrode arrays (MEAs) and the neuronal differentiation of stem cells offers the capability to study human neuronal networks from patient or engineered human cell lines. Here, we use MEA-based assays to probe synaptic function and network interactions of hiPSC-deri...

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Detalles Bibliográficos
Autores principales: Plumbly, William, Brandon, Nick, Deeb, Tarek Z., Hall, Jeremy, Harwood, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761148/
https://www.ncbi.nlm.nih.gov/pubmed/31554851
http://dx.doi.org/10.1038/s41598-019-50226-9