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Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome

Fragile X Syndrome (FXS), a common inheritable form of intellectual disability, is known to alter neocortical circuits. However, its impact on the diverse synapse types comprising these circuits, or on the involvement of astrocytes, is not well known. We used immunofluorescent array tomography to qu...

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Detalles Bibliográficos
Autores principales: Simhal, Anish K., Zuo, Yi, Perez, Marc M., Madison, Daniel V., Sapiro, Guillermo, Micheva, Kristina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761194/
https://www.ncbi.nlm.nih.gov/pubmed/31554841
http://dx.doi.org/10.1038/s41598-019-50240-x