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c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in bladder cancer correlating with cancer progression and invasion. However, the mechanisms underlying HGF/c-MET-mediated invasion in bladder cancer r...

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Detalles Bibliográficos
Autores principales: Sim, Wen Jing, Iyengar, Prasanna Vasudevan, Lama, Dilraj, Lui, Sarah Kit Leng, Ng, Hsien Chun, Haviv-Shapira, Lior, Domany, Eytan, Kappei, Dennis, Tan, Tuan Zea, Saei, Azad, Jaynes, Patrick William, Verma, Chandra Shekhar, Kumar, Alan Prem, Rouanne, Mathieu, Ha, Hong Koo, Radulescu, Camelia, ten Dijke, Peter, Eichhorn, Pieter Johan Adam, Thiery, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761206/
https://www.ncbi.nlm.nih.gov/pubmed/31554791
http://dx.doi.org/10.1038/s41467-019-12241-2