Mutational Analysis of Sigma-1 Receptor’s Role in Synaptic Stability

Sigma-1 receptor (S1R) is an endoplasmic reticulum (ER) resident transmembrane protein. In our previous experiments, we demonstrated neuroprotective effects of pridopidine, an agonist of S1R, in cellular and animal models of Huntington’s disease (HD) and Alzheimer’s disease (AD). Consistent with pre...

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Detalles Bibliográficos
Autores principales: Ryskamp, Daniel A., Zhemkov, Vladimir, Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761230/
https://www.ncbi.nlm.nih.gov/pubmed/31607852
http://dx.doi.org/10.3389/fnins.2019.01012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761230/
https://www.ncbi.nlm.nih.gov/pubmed/31607852
http://dx.doi.org/10.3389/fnins.2019.01012

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