Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut

Epithelia are exposed to diverse types of stress and damage from pathogens and the environment, and respond by regenerating. Yet, the proximal mechanisms that sense epithelial damage remain poorly understood. Here we report that p38 signaling is activated in adult Drosophila midgut enterocytes in re...

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Detalles Bibliográficos
Autores principales: Patel, Parthive H., Pénalva, Clothilde, Kardorff, Michael, Roca, Marianne, Pavlović, Bojana, Thiel, Anja, Teleman, Aurelio A., Edgar, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761285/
https://www.ncbi.nlm.nih.gov/pubmed/31554796
http://dx.doi.org/10.1038/s41467-019-12336-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761285/
https://www.ncbi.nlm.nih.gov/pubmed/31554796
http://dx.doi.org/10.1038/s41467-019-12336-w

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