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Elimination of Reference Mapping Bias Reveals Robust Immune Related Allele-Specific Expression in Crossbred Sheep

Pervasive allelic variation at both gene and single nucleotide level (SNV) between individuals is commonly associated with complex traits in humans and animals. Allele-specific expression (ASE) analysis, using RNA-Seq, can provide a detailed annotation of allelic imbalance and infer the existence of...

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Detalles Bibliográficos
Autores principales: Salavati, Mazdak, Bush, Stephen J., Palma-Vera, Sergio, McCulloch, Mary E. B., Hume, David A., Clark, Emily L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761296/
https://www.ncbi.nlm.nih.gov/pubmed/31608110
http://dx.doi.org/10.3389/fgene.2019.00863