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Elimination of Reference Mapping Bias Reveals Robust Immune Related Allele-Specific Expression in Crossbred Sheep
Pervasive allelic variation at both gene and single nucleotide level (SNV) between individuals is commonly associated with complex traits in humans and animals. Allele-specific expression (ASE) analysis, using RNA-Seq, can provide a detailed annotation of allelic imbalance and infer the existence of...
Autores principales: | Salavati, Mazdak, Bush, Stephen J., Palma-Vera, Sergio, McCulloch, Mary E. B., Hume, David A., Clark, Emily L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761296/ https://www.ncbi.nlm.nih.gov/pubmed/31608110 http://dx.doi.org/10.3389/fgene.2019.00863 |
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