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PLS3 Overexpression Delays Ataxia in Chp1 Mutant Mice

Many neurodegenerative disorders share common pathogenic pathways such as endocytic defects, Ca(2+) misregulation and defects in actin dynamics. Factors acting on these shared pathways are highly interesting as a therapeutic target. Plastin 3 (PLS3), a proven protective modifier of spinal muscular a...

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Detalles Bibliográficos
Autores principales: Janzen, Eva, Wolff, Lisa, Mendoza-Ferreira, Natalia, Hupperich, Kristina, Delle Vedove, Andrea, Hosseinibarkooie, Seyyedmohsen, Kye, Min Jeong, Wirth, Brunhilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761326/
https://www.ncbi.nlm.nih.gov/pubmed/31607845
http://dx.doi.org/10.3389/fnins.2019.00993