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Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis
Sphingosine-1-phosphate receptor subtype 1 (S1P(1)) is essential for lymphocyte egress from lymphoid organs into systemic circulation and provides a well-defined drug target for autoimmune disorders. IMMH001, also called SYL930, is a specific S1P(1)/S1P(4)/S1P(5) modulator. Here, we investigated the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761374/ https://www.ncbi.nlm.nih.gov/pubmed/31607926 http://dx.doi.org/10.3389/fphar.2019.01085 |