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Design and optimization of crocetin loaded PLGA nanoparticles against diabetic nephropathy via suppression of inflammatory biomarkers: a formulation approach to preclinical study
Diabetic nephropathy (DN) is a serious complication of diabetes mellitus whose expand process is linked with the fibrosis, renal hypertrophy and inflammation. The current study was to formulate and optimize the nano-formulation of crocetin (CT-PLGA-NPs) against Streptozotocin-induced renal nephropat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761602/ https://www.ncbi.nlm.nih.gov/pubmed/31524015 http://dx.doi.org/10.1080/10717544.2019.1642417 |