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Principles of tRNA(Ala) Selection by Alanyl–tRNA Synthetase Based on the Critical G3·U70 Base Pair
[Image: see text] Throughout evolution, the presence of a single G3·U70 mismatch in the acceptor stem of tRNA(Ala) is the major determinant for aminoacylation with alanine by alanyl–tRNA synthetase (AlaRS). Recently reported crystal structures of the complexes AlaRS–tRNA(Ala)/G3·U70 and AlaRS–tRNA(A...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761608/ https://www.ncbi.nlm.nih.gov/pubmed/31572855 http://dx.doi.org/10.1021/acsomega.9b01827 |