Inhibition of Senescence‐Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction

BACKGROUND: Myocardial infarction results in a large‐scale cardiomyocyte loss and heart failure due to subsequent pathological remodeling. Whereas zebrafish and neonatal mice have evident cardiomyocyte expansion following injury, adult mammalian cardiomyocytes are principally nonproliferative. Despi...

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Detalles Bibliográficos
Autores principales: Alam, Perwez, Haile, Bereket, Arif, Mohammed, Pandey, Raghav, Rokvic, Miso, Nieman, Michelle, Maliken, Bryan D., Paul, Arghya, Wang, Yi‐Gang, Sadayappan, Sakthivel, Ahmed, Rafeeq P. H., Kanisicak, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761626/
https://www.ncbi.nlm.nih.gov/pubmed/31315484
http://dx.doi.org/10.1161/JAHA.119.012089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761626/
https://www.ncbi.nlm.nih.gov/pubmed/31315484
http://dx.doi.org/10.1161/JAHA.119.012089

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