Inhibition of Senescence‐Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction

BACKGROUND: Myocardial infarction results in a large‐scale cardiomyocyte loss and heart failure due to subsequent pathological remodeling. Whereas zebrafish and neonatal mice have evident cardiomyocyte expansion following injury, adult mammalian cardiomyocytes are principally nonproliferative. Despi...

Descripción completa

Detalles Bibliográficos
Autores principales: Alam, Perwez, Haile, Bereket, Arif, Mohammed, Pandey, Raghav, Rokvic, Miso, Nieman, Michelle, Maliken, Bryan D., Paul, Arghya, Wang, Yi‐Gang, Sadayappan, Sakthivel, Ahmed, Rafeeq P. H., Kanisicak, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761626/
https://www.ncbi.nlm.nih.gov/pubmed/31315484
http://dx.doi.org/10.1161/JAHA.119.012089

Ejemplares similares

Ejemplares similares