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Soluble Neprilysin in the General Population: Clinical Determinants and Its Relationship to Cardiovascular Disease

BACKGROUND: Neprilysin is a metalloprotease involved in proteolysis of numerous peptides, including natriuretic peptides, and is of prognostic and therapeutic importance in heart failure with reduced ejection fraction. No studies have investigated circulating neprilysin in the community, its clinica...

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Detalles Bibliográficos
Autores principales: Reddy, Yogesh N. V., Iyer, Seethalakshmi R., Scott, Christopher G., Rodeheffer, Richard J., Bailey, Kent, Jenkins, Gregory, Batzler, Anthony, Redfield, Margaret M., Burnett, John C., Pereira, Naveen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761669/
https://www.ncbi.nlm.nih.gov/pubmed/31345101
http://dx.doi.org/10.1161/JAHA.119.012943