Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation

BACKGROUND: DNA methylation (DNAm) is a critical regulator of both development and cellular identity and shows unique patterns in neurons. To better characterize maturational changes in DNAm patterns in these cells, we profile the DNAm landscape at single-base resolution across the first two decades...

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Detalles Bibliográficos
Autores principales: Price, Amanda J., Collado-Torres, Leonardo, Ivanov, Nikolay A., Xia, Wei, Burke, Emily E., Shin, Joo Heon, Tao, Ran, Ma, Liang, Jia, Yankai, Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Jaffe, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761727/
https://www.ncbi.nlm.nih.gov/pubmed/31554518
http://dx.doi.org/10.1186/s13059-019-1805-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761727/
https://www.ncbi.nlm.nih.gov/pubmed/31554518
http://dx.doi.org/10.1186/s13059-019-1805-1

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