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Spatial and temporal regulation of the endoproteolytic activity of the SPS-sensor–controlled Ssy5 signaling protease
The Saccharomyces cerevisiae Ssy5 signaling protease is a core component of the plasma membrane (PM)–localized SPS (Ssy1-Ptr3-Ssy5) sensor. In response to extracellular amino acids, the SPS-sensor orchestrates the proteasomal degradation of the inhibitory Ssy5 prodomain. The unfettered catalytic (Ca...
Autores principales: | Martins, António, Ring, Andreas, Omnus, Deike J., Heessen, Stijn, Pfirrmann, Thorsten, Ljungdahl, Per O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761765/ https://www.ncbi.nlm.nih.gov/pubmed/31461372 http://dx.doi.org/10.1091/mbc.E19-02-0096 |
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