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A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network

Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structures, including 10 that assemble within mitochondri...

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Detalles Bibliográficos
Autores principales: Noree, Chalongrat, Begovich, Kyle, Samilo, Dane, Broyer, Risa, Monfort, Elena, Wilhelm, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761767/
https://www.ncbi.nlm.nih.gov/pubmed/31483745
http://dx.doi.org/10.1091/mbc.E19-04-0224