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DNA damage triggers increased mobility of chromosomes in G1-phase cells

During S phase in Saccharomyces cerevisiae, chromosomal loci become mobile in response to DNA double-strand breaks both at the break site (local mobility) and throughout the nucleus (global mobility). Increased nuclear exploration is regulated by the recombination machinery and the DNA damage checkp...

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Detalles Bibliográficos
Autores principales: Smith, Michael J., Bryant, Eric E., Joseph, Fraulin J., Rothstein, Rodney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761769/
https://www.ncbi.nlm.nih.gov/pubmed/31483739
http://dx.doi.org/10.1091/mbc.E19-08-0469