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Targeting trimeric transmembrane domain 5 of oncogenic latent membrane protein 1 using a computationally designed peptide

Protein–protein interactions are involved in diverse biological processes. These interactions are therefore vital targets for drug development. However, the design of peptide modulators targeting membrane-based protein–protein interactions is a challenging goal owing to the lack of experimentally-de...

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Detalles Bibliográficos
Autores principales: Wang, Yibo, Peng, Yinghua, Zhang, Bo, Zhang, Xiaozheng, Li, Hongyuan, Wilson, Andrew J., Mineev, Konstantin S., Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761861/
https://www.ncbi.nlm.nih.gov/pubmed/31588309
http://dx.doi.org/10.1039/c9sc02474c