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Aza-proline effectively mimics l-proline stereochemistry in triple helical collagen
The prevalence of l-amino acids in biomolecules has been shown to have teleological importance in biomolecular structure and self-assembly. Recently, biophysical studies have demonstrated that natural l-amino acids can be replaced with non-natural achiral aza-amino acids in folded protein structures...
Autores principales: | Kasznel, Alexander J., Harris, Trevor, Porter, Nicholas J., Zhang, Yitao, Chenoweth, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761869/ https://www.ncbi.nlm.nih.gov/pubmed/31588264 http://dx.doi.org/10.1039/c9sc02211b |
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