Introduction of the α-ketoamide structure: en route to develop hydrogen peroxide responsive prodrugs

Leveraging the elevated levels of hydrogen peroxide (H(2)O(2)) in cancer, inflammatory diseases and cardiovascular disorders, H(2)O(2)-activated promoieties have been widely used in drugs and biomaterials design. However, the overwhelming majority of the promoieties only share the common structure o...

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Detalles Bibliográficos
Autores principales: Meng, Tingting, Han, Jing, Zhang, Pengfei, Hu, Jing, Fu, Junjie, Yin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761880/
https://www.ncbi.nlm.nih.gov/pubmed/31588282
http://dx.doi.org/10.1039/c9sc00910h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761880/
https://www.ncbi.nlm.nih.gov/pubmed/31588282
http://dx.doi.org/10.1039/c9sc00910h

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