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Introduction of the α-ketoamide structure: en route to develop hydrogen peroxide responsive prodrugs

Leveraging the elevated levels of hydrogen peroxide (H(2)O(2)) in cancer, inflammatory diseases and cardiovascular disorders, H(2)O(2)-activated promoieties have been widely used in drugs and biomaterials design. However, the overwhelming majority of the promoieties only share the common structure o...

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Detalles Bibliográficos
Autores principales:	Meng, Tingting, Han, Jing, Zhang, Pengfei, Hu, Jing, Fu, Junjie, Yin, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761880/ https://www.ncbi.nlm.nih.gov/pubmed/31588282 http://dx.doi.org/10.1039/c9sc00910h

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