The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis

The popularity of NHCs in transition metal catalysis has prompted the development of chiral versions as electron-rich neutral stereodirecting ancillary ligands for enantioselective transformations. Herein we demonstrate that cyclic (alkyl)(amino)carbene (CAAC) ligands can also engage in asymmetric t...

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Autores principales: Pichon, Delphine, Soleilhavoup, Michele, Morvan, Jennifer, Junor, Glen P., Vives, Thomas, Crévisy, Christophe, Lavallo, Vincent, Campagne, Jean-Marc, Mauduit, Marc, Jazzar, Rodolphe, Bertrand, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761915/
https://www.ncbi.nlm.nih.gov/pubmed/31588330
http://dx.doi.org/10.1039/c9sc02810b
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author Pichon, Delphine
Soleilhavoup, Michele
Morvan, Jennifer
Junor, Glen P.
Vives, Thomas
Crévisy, Christophe
Lavallo, Vincent
Campagne, Jean-Marc
Mauduit, Marc
Jazzar, Rodolphe
Bertrand, Guy
author_facet Pichon, Delphine
Soleilhavoup, Michele
Morvan, Jennifer
Junor, Glen P.
Vives, Thomas
Crévisy, Christophe
Lavallo, Vincent
Campagne, Jean-Marc
Mauduit, Marc
Jazzar, Rodolphe
Bertrand, Guy
author_sort Pichon, Delphine
collection PubMed
description The popularity of NHCs in transition metal catalysis has prompted the development of chiral versions as electron-rich neutral stereodirecting ancillary ligands for enantioselective transformations. Herein we demonstrate that cyclic (alkyl)(amino)carbene (CAAC) ligands can also engage in asymmetric transformations, thereby expanding the toolbox of available chiral carbenes.
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spelling pubmed-67619152019-10-04 The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis Pichon, Delphine Soleilhavoup, Michele Morvan, Jennifer Junor, Glen P. Vives, Thomas Crévisy, Christophe Lavallo, Vincent Campagne, Jean-Marc Mauduit, Marc Jazzar, Rodolphe Bertrand, Guy Chem Sci Chemistry The popularity of NHCs in transition metal catalysis has prompted the development of chiral versions as electron-rich neutral stereodirecting ancillary ligands for enantioselective transformations. Herein we demonstrate that cyclic (alkyl)(amino)carbene (CAAC) ligands can also engage in asymmetric transformations, thereby expanding the toolbox of available chiral carbenes. Royal Society of Chemistry 2019-07-06 /pmc/articles/PMC6761915/ /pubmed/31588330 http://dx.doi.org/10.1039/c9sc02810b Text en This journal is © The Royal Society of Chemistry 2019 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)
spellingShingle Chemistry
Pichon, Delphine
Soleilhavoup, Michele
Morvan, Jennifer
Junor, Glen P.
Vives, Thomas
Crévisy, Christophe
Lavallo, Vincent
Campagne, Jean-Marc
Mauduit, Marc
Jazzar, Rodolphe
Bertrand, Guy
The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title_full The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title_fullStr The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title_full_unstemmed The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title_short The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
title_sort debut of chiral cyclic (alkyl)(amino)carbenes (caacs) in enantioselective catalysis
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761915/
https://www.ncbi.nlm.nih.gov/pubmed/31588330
http://dx.doi.org/10.1039/c9sc02810b
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