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Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species
The Dot/Icm type IVB secretion system of Legionella pneumophila is essential for its pathogenesis by delivering >300 effector proteins into the host cell. However, their precise secretion mechanism and which components interact with the host cell is only partly understood. Here, we undertook evol...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761968/ https://www.ncbi.nlm.nih.gov/pubmed/31504472 http://dx.doi.org/10.1093/gbe/evz186 |