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Parameter balancing: consistent parameter sets for kinetic metabolic models

SUMMARY: Measured kinetic constants are key input data for metabolic models, but they are often uncertain, inconsistent and incomplete. Parameter balancing translates such data into complete and consistent parameter sets while accounting for predefined ranges and physical constraints. Based on Bayes...

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Detalles Bibliográficos
Autores principales: Lubitz, Timo, Liebermeister, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761981/
https://www.ncbi.nlm.nih.gov/pubmed/30793200
http://dx.doi.org/10.1093/bioinformatics/btz129