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Destin: toolkit for single-cell analysis of chromatin accessibility

SUMMARY: Single-cell assay of transposase-accessible chromatin followed by sequencing (scATAC-seq) is an emerging new technology for the study of gene regulation with single-cell resolution. The data from scATAC-seq are unique—sparse, binary and highly variable even within the same cell type. As suc...

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Detalles Bibliográficos
Autores principales: Urrutia, Eugene, Chen, Li, Zhou, Haibo, Jiang, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761983/
https://www.ncbi.nlm.nih.gov/pubmed/30821321
http://dx.doi.org/10.1093/bioinformatics/btz141