Construction and optimization of a base editor based on the MS2 system

BACKGROUND: Catalytic defect Cas9‐cytosine deaminase fusion is widely used in base editing. The Multiple copy numbers of the MS2 binding site (MBS) can recruit multiple MS2 coat proteins (MCPs), which are usually applied to amplify signals. Our study aimed to apply the MS2 signal amplification syste...

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Detalles Bibliográficos
Autores principales: Zhang, Shuzhen, Feng, Songjie, Jiang, Wen, Huang, Xingxu, Chen, Jieping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762045/
https://www.ncbi.nlm.nih.gov/pubmed/31773094
http://dx.doi.org/10.1002/ame2.12080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762045/
https://www.ncbi.nlm.nih.gov/pubmed/31773094
http://dx.doi.org/10.1002/ame2.12080

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