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Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation
Seizures can induce endoplasmic reticulum (ER) stress, and sustained ER stress contributes to neuronal death after epileptic seizures. Despite the recent debate on whether inhibiting ER stress can reduce neuronal death after seizures, whether and how ER stress impacts neural activity and seizures re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762060/ https://www.ncbi.nlm.nih.gov/pubmed/31557161 http://dx.doi.org/10.1371/journal.pgen.1008364 |