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Heat shock-induced chaperoning by Hsp70 is enabled in-cell

Recent work has shown that weak protein-protein interactions are susceptible to the cellular milieu. One case in point is the binding of heat shock proteins (Hsps) to substrate proteins in cells under stress. Upregulation of the Hsp70 chaperone machinery at elevated temperature was discovered in the...

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Detalles Bibliográficos
Autores principales: Guin, Drishti, Gelman, Hannah, Wang, Yuhan, Gruebele, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762143/
https://www.ncbi.nlm.nih.gov/pubmed/31557226
http://dx.doi.org/10.1371/journal.pone.0222990