Potential impact of efflux pump genes in mediating rifampicin resistance in clinical isolates of Mycobacterium tuberculosis from India

Despite the consideration of chromosomal mutations as the major cause of rifampicin (RIF) resistance in M. tuberculosis, the role of other mechanisms such as efflux pumps cannot be ruled out. We evaluated the role of four efflux pumps viz., MmpL2 (Rv0507), MmpL5 (Rv0676c), Rv0194 and Rv1250 in provi...

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Detalles Bibliográficos
Autores principales: Narang, Anshika, Garima, Kushal, Porwal, Shraddha, Bhandekar, Archana, Shrivastava, Kamal, Giri, Astha, Sharma, Naresh Kumar, Bose, Mridula, Varma-Basil, Mandira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762166/
https://www.ncbi.nlm.nih.gov/pubmed/31557231
http://dx.doi.org/10.1371/journal.pone.0223163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762166/
https://www.ncbi.nlm.nih.gov/pubmed/31557231
http://dx.doi.org/10.1371/journal.pone.0223163

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